The statement comes after some Twitter users have called on the company to ban President Trump for tweets that they say encourage violence, even stoking fears of a nuclear war between the USA and North Korea.
Ultimately, Twitter said Friday, prohibiting world leaders from using its service would be ineffective, because it would "not silence" them but "would certainly hamper necessary discussion around their words and actions".
The protests come in response to Trump's tweet regarding a nuclear button that is "bigger and more powerful" than the North Korean leader's.
The company also sought to counter assertions that controversial figures like Trump were kept on the platform largely because they helped Twitter's bottom line. "Elected world leaders play a critical role in that conversation due to their outsized impact on our society", they wrote.
Reaffirming its somewhat unclear terms of service, Twitter said that world leaders are effectively above being blocked from the service because their tweets are "important information people should be able to see and debate".
Friday's announcement comes less than a month after Twitter began enforcing new rules aimed at filtering out "hateful" and "abusive" content on the social network, including messages which promote or glorify violence.
In an interview with United States broadcaster Voice of America, Pence said the president's leadership on the world stage has resulted in "measurable progress", especially on the issue of North Korea's nuclear and ballistic missile programs. No one person's account drives Twitter's growth, or influences these decisions.
It added: "We work hard to remain unbiased with the public interest in mind".
A White House spokeswoman said she did not expect there to be any White House comment on the Twitter statement.
"Freaked out by Trump's tweet threatening nuclear war with #NorthKorea?" tweeted Rep. Ted Lieu, D-Los Angeles.