But in an interview Monday, former Israel Air Force Commander Eitan Ben Eliyahu said that Israel could very well have been involved in the attack. Reports said that Trump's comment has come a year and a day after the U.S. fired cruise missiles at a Syrian airbase in retaliation for a deadly sarin gas attack in 2017.
Russia's Defense Ministry said two Israeli aircraft targeted the base Monday, firing eight missiles.
But Israeli officials said the Tiyas, or T-4, air base was being used by troops from Iran and that Israel would not accept such a presence in Syria by its arch foe. The use of chemical weapons in April 2017 provoked a US missile strike, the first direct American hit on Bashar al-Assad's regime since the conflict in Syria began in March 2011.
Israel has struck Syrian army locations many times in the course of the conflict, hitting convoys and bases of Iranian-backed militias that fight alongside Syrian President Bashar al Assad's forces. The Pentagon later issued a statement saying, "At this time, the Department of Defense is not conducting airstrikes in Syria".
Syrian opposition activists and local rescuers said on Sunday that the suspected attack from the previous day against the last remaining foothold of the rebels in the eastern suburbs of Damascus killed at least 40 people.
AP quoted SANA saying it was "likely to be an American aggression" though USA officials told the organization no American military action had been taken.
"Many dead, including women and children, in mindless CHEMICAL attack in Syria", Trump tweeted on Saturday.
Russia's UN ambassador, Vassily Nebenzia, urged inspectors from the watchdog agency to fly to Syria's capital today and visit the site in a nearby rebel-held town.He denied any attack occurred, telling the UN Security Council that experts from Russia's military radiological, biological and chemical unit went to the site and found no chemical substances on the ground, no dead, and no poisoned people in hospitals.
Speaking to 103 Radio, Ben Eliyahu said that if the attack was in retaliation for the weekend assault on civilians with gas weapons, "the United States would have had a hard time acting so quickly, unless it had a ship or planes in or over the Mediterranean".
President Donald Trump meanwhile blasted Russian President Vladimir Putin and the government of Iran for backing Assad, whom Trump dubbed "Animal Assad", in the country's years-long civil war.
When asked about the explosions, an Israeli spokeswoman declined to comment. Israel hit the base, known as T4, in February, after it said an Iranian drone that violated Israeli airspace took off from it.
Ultimately, however, the Syrian government agreed to destroy its stockpiles of the weapon, and the USA did not respond with strikes.
Syria, backed its Russian and Iranian allies, dismissed United States allegations of its responsibility as "fabrications".
Trump has not left out anyone in the blame game against the president of Syria.
An image from a video released by the Douma City Coordination Committee shows a girl being sprayed with water Saturday following an alleged chemical attack on the rebel-held town. The European Union also said evidence pointed to the use of chemical weapons by Assad's forces.