Benjamin Franklin, located in New Orleans' Gentilly neighborhood, also ranked No. 81 nationally with a graduation rate of more than 95 percent and a 86.9 score for college readiness.
"We are very proud to be nationally recognized as a high-achieving school by U.S. News", Principal Mark Wells said. "Congratulations and thank you for your hard work!"
"The hard work, dedication, and commitment to high-quality education that is shown on a daily basis as you walk through the hallways and classrooms of both our high schools are what makes Sylvania an fantastic place to call home and raise a family", he said.
Within San Diego, most top-performing districts and campuses have lower percentages of students who are English learners or come from low-income families - factors which typically affect test scores and graduation rates. Only 2 percent of schools in the country, including Ottawa Hills, received a gold star.
Each of Arkansas' top three high schools this year are open-enrollment charter schools.
The majority of the rankings were based on a combination of metrics including performance on state proficiency tests, graduation rates, and performance on Advanced Placement tests.
The Tucson Unified School District's University High School placed 27th in the country, according to the study, down from 15th past year.
"With this in mind, we define a "best" high school as one that best serves all of its students", he said in a statement.
The 2018 high school rankings were just released by the publication.
At No. 39, Elizabethtown High School ranked the highest in the state out of area schools.