A volcano eruption has killed at least six people in Central America.
One village was extremely affected by running lava causing deaths and injuries.
"We are evacuating and rescuing people and have reports of 20 wounded, six dead and disappeared", said Mr Cabanas.
A towering cloud of smoke from Volcan de Fuego, Spanish for "volcano of fire", 44 kilometers from Guatemala City has also blanketed nearby villages in heavy ash.
The Volcan de Fuego in Guatemala has erupted, shooting ash 10 km into the air and blanketing villages within 25km of the crater.
Guatemala's national disaster coordinator, Sergio Cabañas, said an undetermined number of people were missing following the eruption of the Volcán de Fuego, about 30 miles from Guatemala City. "There are injured, burned and dead people", he said.
Ash has effected not only Guatemala City but the departments of Sacatepequez, Chimaltenango, Escuintla, and the popular tourist destination colonial town Antigua.
The Fuego eruption resulted in closure of La Aurora airport of the country's capital of Guatemala City, the TV Azteca broadcaster reported on Sunday citing the Guatemalan Coordinating Agency for Disaster Reduction (CONRED).
The Guatemalan military said it was providing assistance including clearing volcanic ash from the airport's runway.
It is the second time the volcano has erupted this year, setting off loud explosions and spewing ash almost four miles into the sky.
The conical Volcan de Fuego reaches an altitude of 3,763 metres above sea level at its peak. "That could cause more mud flows and nearby rivers to burst their banks", said Eddy Sanchez, director of Guatemala's seismological, volcanic and meteorological institute.
The river of lava has reportedly changed direction and is now heading toward a small town.
Guatemala's disaster agency said 3,100 people had evacuated nearby communities, and the eruption was affecting an area with a population of about 1.7 million people.
Officials have advised citizens to wear masks due to falling ash, which has been raining down in four of Guatemala's administrative regions.