Cristiano Ronaldo and Lionel Messi are once again nominated for Ballon d'Or award.
The teenager is also on the 10-player shortlist for the inaugural Kopa Trophy, a new prize for the best player under 21, which is judged by stars including Cristiano Ronaldo and Messi.
Ronaldo, now at Juventus, won the Champions League for the third season in a row with Madrid, while De Bruyne inspired Manchester City's Premier League and EFL Cup double before a strong World Cup showing.
Antoine Griezmann, a World Cup victor with France and Europa League champion at Atletico Madrid, is nominated alongside global teammates, Chelsea midfielder N'Golo Kante, Manchester United's Paul Pogba and PSG's Kylian Mbappe.
Liverpool's Brazilian forward Roberto Firmino and Uruguay's rugged defender Diego Godin of Atletico Madrid also got the nod.
Others are Liverpool goalkeeper Alisson, Real Madrid striker Karim Benzema and Paris St-Germain attacker Edinson Cavani.
For the first time, a Ballon d'Or for women players will be awarded this year, with the nominees to be announced later Monday.
Kylian Mbappe, who hit four goals in 13 minutes on Sunday in the rout over Lyon, remains in the hunt for the award after ending his season with a World Cup winners' medal with France.
The Ballon d'Or, which was first won by Englishman Stanley Matthews in 1956, is decided by a ballot of journalists from around the world.