However, he has a 2-6 record against Federer with his most recent win over the 20-time major champion coming in 2014.
He had won his previous three finals, and said his 100 percent record helped him when he stepped on court against the 14-time Grand Slam champion.
Federer won 28/29 first serves, saved the only break point he faced, and took full advantage of the fast courts to attack the front of the court with plenty of success. He was given a huge ovation by the crowd after his win.
"We had epic matches throughout our rivalry but this one definitely ranks as one of the best", Djokovic said. "And this title, it's a good year-end I would say", Khachanov said. Following his triumph at the All England Club, he has won Cincinnati Masters, US Open and Shanghai Masters. "And maybe I'm not crying, but still I'm really happy". "I missed all the second returns". His long backhand in the 10th game earned the Russian hopeful a ground-breaking title of career.
When in more peril at break point down at 3-3, he delivered an fantastic game-saving backhand at full stretch, which perhaps helped break Cilic's spirit.
Djokovic broke for 3-1 in the second set and did not look back. I was a break down in the third set.
"It was a spectacular match", Djokovic told Sky Sports.
"I'm still struggling. It's kind of a flu". "My priority is London, but now I am so far into the tournament I'll just give it a go and hope things click for me".
Khachanov, the victor at last month's Kremlin Cup in Moscow, demolished out-of-sorts fourth seed Alexander Zverev of Germany 6-1, 6-2 while Thiem knocked out defending champion Jack Sock, the 16th-seeded American, 4-6, 6-4, 6-4.
Zverev had treatment on his right shoulder late in the first set and made a string of unforced errors.
Khachanov soon snatched the break back and, after edging ahead at 6-5 with another break, sealed the set in 58 minutes with his third ace.
"I told him my shoulder is hurting and that his uncle, or something, that he's going a bit insane", Zverev said. And what more can I ask for?
The Russian, who had prevailed in just three of his 19 encounters against players in the top 10, became the third different victor of a 1000 series event this season, could still take part in the ATP Tour Finals in London as a second alternate.
Russia's Karen Khachanov celebrates after winning against Austria's Dominic Thiem at the end of their men's singles semi-final tennis match on day six of Paris Masters tournament in Paris, on November 3, 2018.